MRESCIENCE.NET
  • Home
  • Downloads Q Two
  • Bullying
  • S. Harassment
  • Abuse
  • 2020-2021 CALENDAR

DNA MUTATIONS

BELL WORK:         
What do you think of when you
​hear the word mutation?









Essential Question:
What are the types of DNA mutations, and what effect
do they have on transcription/translation?

Instructional Focus / TLW:
Explain how DNA mutations modify proteins.















BEFORE WE MOVE ON....
​THINGS WE ALREADY KNOW THAT WILL HELP...

In DNA:  Replication
A-T-C-G 
T-A-G-C


DNA TO mRNA: Transcription
A-T-C-G        Use codon wheel.
U-A-G-C 
        RNA HAS "U" NOT "T"

mRNA TO tRNA:   Translation /polypeptide
U-A-G-C      
A-U-C-G

​









MUTATION FACTS:
1. A mutation is a change that occurs in our DNA sequence.
2. Mutations can occur during DNA replication.
3. There are several types of DNA mutations.
4. DNA mutations may or may not cause a problem.
















We will investigate several
types of DNA Mutations:

1. Point
2. Substitution
3. Inversion
4. Insertion / Frameshift
5. Deletion / Frameshift
* And later analyze for missense and nonsense mutations...

missense = a change in one amino acid in a protein
nonsense = codon is changed to a premature stop


 /








​Instructional Focus / TLW:
Explain how DNA mutations modify proteins.
1. Complete the POINT mutation handout. USE A CODON WHEEL.
We will compare lines 2, 3, 4, 5, 6, and 7 to line 1.
Line one is the "NORMAL" DNA.

Picture


​Instructional Focus / TLW:
Explain how DNA mutations modify proteins.
1. Complete the SUBSTITUTION mutation handout. USE A CODON WHEEL.
We will compare lines 2, 3, 4, 5, 6, and 7 to line 1.
Line one is the "NORMAL" DNA.

Picture






THE ONLY THING YOU TURN IN TODAY IS THE TICKET / QUIZ.
HIGH-QUALITY COMPLETE ANSWERS ARE EXPECTED.
TICKET / QUIZ:
1. List​ 3 things that you learned today.
2. Explain or draw: How to recognize a point mutation?
3. Explain or draw: How to recognize a substitution mutation?
4. Explain how DNA mutations modify proteins. 
TURN IN TICKET-QUIZ---GREEN CONTAINER-TOP OF FILE CABINET.

KEEP ALL MUTATION SHEETS UNTIL END OF CLASS THURSDAY.





​

Cordova High School

CHS Official Site
CHS Library

Resources:

SHELBY COUNTY SCHOOLS
MAP TO CHS

Motto:

"The strength of the pack is the wolf...
  The strength of the wolf is the pack."
​©
COPYRIGHT 2015
ALL RIGHTS RESERVED.
  • Home
  • Downloads Q Two
  • Bullying
  • S. Harassment
  • Abuse
  • 2020-2021 CALENDAR